The UK has now notified officially its decision to leave the European Union and triggered article 50. BusinessEurope and its 40 member federations from 34 European countries have published a “Preliminary reaction to the triggering of Article 50”. BusinessEurope stands ready to play a constructive role in the search of solutions to establish a sound and balanced new model for EU-UK relations. It is in the interest of both the European Union and the United Kingdom to pursue mutually beneficial relations in the future, in a level playing field environment. The exit of the UK from the EU must be smooth. Negotiations should be led in a true spirit of partnership and mutual loyalty.